唐惠儒

发布者:王诗铭发布时间:2021-05-06浏览次数:1685

教师基本信息

职称:教授

电子邮箱:huiru_tang@fudan.edu.cn

办公地点:公司生科院D105

办公电话:021-31246725


个人简介

男,1966年生,国家杰出青年科学基金获得者、英国皇家化学会会士、公司特聘教授、国家重点研发计划项目首席。1986年获西北轻工业学院(现陕西科技大学)学士学位,1994年获伦敦大学博士学位。1992-2000年英国BBSRC食品研究所Research ScientistSenior Scientist2001-05年英国帝国理工学院生物医学部Senior Scientist2005-14年中科院武汉物数所研究员、博士生导师、研究部副主任、中科院生物磁共振分析重点实验室创建主任。2014年加盟永利集团304am官方入口。曾任英国NHS、科技部973及蛋白质重大计划等评审专家、J Proteome Res编委。在NaturePNAS等上发表SCI论文200余篇,被引1万余次(h指数~58)。获批发明专利5项。部分工作被ScienceNature等作为“研究亮点”专文评述。现任中国生物物理学会理事、代谢组学分会会长、自由基生物学及医学分会常务理事、生物磁共振专委会委员,中国抗癌协会肿瘤代谢专业委员会常务理事,中国营养学会基础营养学分会理事,MetabolomicsCurr MetabolomicsArch Pharm和《基础医学与临床》等编委,Nutrition & MetabolismPhenomics等副主编。

Personal website: http://www.metabolome.cn/


研究方向

研究代谢物结构与功能30余年,正发展高通量超灵敏代谢组学技术、代谢组与转录组/蛋白质组/微生物组等数据整合技术,研究肥胖等重大疾病发生发展的代谢组基础。曾主持完成国家杰出青年科学基金、国家重点研发计划、国家自然科学基金重大项目、肥胖等973项目课题多项。现承担国家创新群体、市级重大专项等课题。


获奖情况

英国皇家化学会会士(2005)、国家杰出青年科学基金(2008)、“新世纪百千万人才工程”国家级人选称号(2009)、王天眷波谱学奖(2010)、武汉市优秀科技工作者(2011)。


代表性论文和论著

  1. * M. Xia, et al, “Insights into contribution of genetic variants towards the susceptibility of MAFLD revealed by the NMR_based lipoprotein profiling”, J Hepatol, 74:974-977, 2021. IF~25.1

  2. * Y. Xu, et al, “Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues”, EMBO J. e108069, 2021. IF~11.6

  3. * M. Wang, et al, “Glucose-mediated proliferation of a gut commensal bacterium promotes Plasmodium infection by increasing mosquito midgut pH”, Cell Rep, 35:108992, 2021. IF~9.4

  4. * Q. Hu, et al, “Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using IPRP-LC-MS/MS”, Talanta, 238:123059, 2022.IF~6.1

  5. * R. Loo, et al, “A feasibility study of metabolic phenotyping of dried blood spot specimens in rural Chinese women exposed to household air pollution”,J Expo Sci Environ Epidemiol, 31:328-344, 2021. IF~5.6

  6. * Z. Zhang, et al, “New types of ATP-grasp ligase are associated with the novel pathway for complicated mycosporine-like amino acid production in desiccation-tolerant cyanobacteria”, Environ Microbiol, 23:6420–6432. 2021.IF~5.5

  7. * Y. An, et al, “Development and validation of an improved probabilistic quotient normalization method for LC/MS- and NMR-based metabonomic analysis”, Chin Chem Lett, 31:1827-1830, 2020. IF~6.8

  8. * J. Xue, et al, “A vitamin-C-derived DNA modification catalysed by an algal TET homologue”, Nature, 569:581–585, 2019IF~50.0

  9. * H. Lin, et al, “Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat model”, J Agric Food Chem, 67:3624-3632. 2019.IF~5.3, 高被引,年均17次】

  10. * J. Gou, et al, “Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis”, Plant J,93:92-106, 2018.IF~6.4

  11. * F. Chen, et al, “Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated with Fusarium graminearum resistance in transgenic Arabidopsis thaliana”,Front Plant Sci, 8:2177, 2018.IF~5.8

  12. * L. Zhang, et al, “Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats”, J Agric Food Chem, 66: 1723−1731, 2018. IF~5.3

  13. * C. Liu, B. Du, F. Hao, H. Lei, Q. Wan, G. He, Y. Wang. H. Tang, "Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants", PBJ, 15:1346, 2017.IF~9.8

  14. * Q. Wan, et al, "Quantitative 13C traces of glucose fate in hepatitis B virus infected hepatocytes", Anal Chem, 89:3293–3299, 2017 IF~7.0

  15. * Y. Kumar, et al, "Fusarium oxysporum mediates systems metabolic reprogramming of chickpea roots as revealed by a combination of proteomics and metabolomics", PBJ,14:1589, 2016IF~9.8

  16. * H. Li, et al, "Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer", Cell Discov, 2:16031, 2016. IF~5.8

  17. * L. Sun, et al, "cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions". Cell Res, 25:429–444, 2015. IF~25.6

  18. * C. Zhang, et al, "Dietary modulation of gut microbiota contributes to alleviation of both genetic and simple obesity in children",eBioMedicine, 2:968-984, 2015. IF~8.1

  19. * L. Zhang, et al, “Selective metabolic effects of gold nanorods on normal and cancer cells and their application in anticancer drug screening”, Biomaterials, 34:7117-7126, 2013. IF~12.5

  20. * M. Li, et al, “Human symbiotic gut microbes specifically modulate metabolic phenotypes”, PNAS, 105:2117-2122, 2008. IF~11.2



论文及引用Full Publication List

https://publons.com/researcher/2776607/huiru-tang/